Tim K Tsang

Tim K Tsang

Assistant Professor, School of Public Health, University of Hong Kong

Paper Title Number 1

Published:

(*joint first author, #corresponding author)

  1. Tsang TK#, Huang X, Wang C, Chen S, Yang B, Cauchemez S, Cowling BJ. The effect of variation of individual infectiousness on SARS-CoV-2 transmission in households. eLife. 2023 Mar 7;12:e82611.

  2. Tsang TK#, Wang C, Tsang NNY, Fang VJ, Perera RAPM, Malik Peiris JS, Leung GM, Cowling BJ, Ip DKM. Impact of host genetic polymorphisms on response to inactivated influenza vaccine in children. NPJ Vaccines. 2023 Feb 20;8(1):21.

  3. Tsang TK#, Huang X, Guo Y, Lau EHY, Cowling BJ, Ip DKM. Monitoring School Absenteeism for Influenza-Like Illness Surveillance: Systematic Review and Meta-analysis. JMIR Public Health Surveill. 2023 Jan 11;9:e41329.

  4. Tsang TK#, Gostic KM, Chen S, Wang Y, Arevalo P, Lau EHY, Cobey S, Cowling BJ. Investigation of impact of childhood immune imprinting on birth year-specific risk of clinical infection during influenza A virus epidemics in Hong Kong. J Infect Dis. 2023 Jan 13:jiad009

  5. Xiong W, Peng L, Tsang TK#, Cowling BJ. Epidemiology of SARS-CoV-2 Omicron BA.5 Infections, Macau, June-July 2022. Emerg Infect Dis. 2023

  6. Ho F, Parag KV, Adam DC, Lau EHY, Cowling BJ, Tsang TK#. Accounting for the Potential of Overdispersion in Estimation of the Time-varying Reproduction Number. Epidemiology. 2023 Mar 1;34(2):201-205

  7. Xie R, Edwards KM, Adam DC, Leung KSM, Tsang TK, Gurung S, Xiong W, Wei X, Ng DYM, Liu GYZ, Krishnan P, Chang LDJ, Cheng SMS, Gu H, Siu GKH, Wu JT, Leung GM, Peiris M, Cowling BJ, Poon LLM, Dhanasekaran V. Resurgence of Omicron BA.2 in SARS-CoV-2 infection-naive Hong Kong. Nat Commun. 2023 Apr 27;14(1):2422

  8. Tsang TK, Perera RAPM, Fang VJ, Wong JY, Shiu EY, So HC, Ip DKM, Malik Peiris JS, Leung GM, Cowling BJ, Cauchemez S. Reconstructing antibody dynamics to estimate the risk of influenza virus infection. Nat Commun. 2022 Mar 23;13(1):1557.

  9. Tsang TK, Lam KT, Liu Y, Fang VJ, Mu X, Leung NHL, Peiris JSM, Leung GM, Cowling BJ, Tu W. Investigation of CD4 and CD8 T cell-mediated protection against influenza A virus in a cohort study BMC Med. 2022 Jul 21;20(1):230.

  10. Tsang TK#, Wang C, Fang VJ, Perera RAPM, So HC, Ip DKM, Peiris JSM, Leung GM, Cauchemez S, Cowling BJ. Indirect Protection from Vaccinating Children against Influenza A Virus Infection in Households. Viruses. 2022 Sep 21;14(10):2097.

  11. Tsang TK, Fang LQ, Zhang A, Jiang FC, Ruan SM, Liu LZ, Cowling BJ, Liu W, Yang Y. Variability in transmission risk of SARS-CoV-2 in close contact settings: A contact tracing study in Shandong Province, China Epidemics. 2022 Mar 9;39:100553

  12. Xiong W, Tsang TK#, Perera RAPM, Leung NHL, Fang VJ, Barr IG, Peiris JSM, Cowling BJ. Biphasic waning of hemagglutination inhibition antibody titers after influenza vaccination in children. J Infect Dis. 2022 Apr 5:jiac117.

  13. Ho F, Tsang TK#, Gao H, Xiao J, Lau EHY, Wong JY, Wu P, Leung GM, Cowling BJ. Restaurant-Based Measures to Control Community Transmission of COVID-19, Hong Kong Emerg Infect Dis. 2022 Mar;28(3):759-761.

  14. Wang C, Huang X, Lau EHY, Cowling BJ, Tsang TK#. Association Between Population-Level Factors and Household Secondary Attack Rate of SARS-CoV-2: A Systematic Review and Meta-analysis. Open Forum Infect Dis. 2022 Dec 16;10(1):ofac676.

  15. Cheung JTL, Tsang TK, Yen HL, Perera RAPM, Mok CKP, Lin YP, Cowling BJ, Peiris M. Determining Existing Human Population Immunity as Part of Assessing Influenza Pandemic Risk Emerg Infect Dis. 2022 May;28(5):977-985.

  16. Yang B, Huang X, Gao H, Leung NH, Tsang TK, Cowling BJ. Immunogenicity, efficacy, and safety of SARS-CoV-2 vaccine dose fractionation: a systematic review and meta-analysis. BMC Med. 2022 Oct 25;20(1):409.

  17. Ali ST, Lau YC, Shan S, Ryu S, Du Z, Wang L, Xu XK, Chen D, Xiong J, Tae J, Tsang TK, Wu P, Lau EHY, Cowling BJ. Prediction of upcoming global infection burden of influenza seasons after relaxation of public health and social measures during the COVID-19 pandemic: a modelling study. Lancet Glob Health. 2022 Nov;10(11):e1612-e1622.

  18. Lin Y, Yang B, Cobey S, Lau EHY, Adam DC, Wong JY, Bond HS, Cheung JK, Ho F, Gao H, Ali ST, Leung NHL, Tsang TK, Wu P, Leung GM, Cowling BJ. Incorporating temporal distribution of population-level viral load enables real-time estimation of COVID-19 transmission Nat Commun. 2022 Mar 3;13(1):1155.

  19. Yang B, Wong IOL, Xiao J, Tsang TK, Liao Q, Cowling BJ. Effectiveness of CoronaVac and BNT162b2 Vaccines Against Severe Acute Respiratory Syndrome Coronavirus 2 Omicron BA.2 Infections in Hong Kong. J Infect Dis. 2022 Oct 17;226(8):1382-1384.

  20. Ryu S, Han C, Kim D, Tsang TK, Cowling BJ, Lee S. Association Between the Relaxation of Public Health and Social Measures and Transmission of the SARS-CoV-2 Omicron Variant in South Korea JAMA Netw Open. 2022 Aug 1;5(8):e2225665.

  21. Tsang TK, Wang C, Yang B, Cauchemez S, Cowling BJ. Using secondary cases to characterize the severity of an emerging or re-emerging infection Nat Commun. 2021 Nov 4;12(1):6372.

  22. Tsang TK#, Wu P, Lau EHY, Cowling BJ. Accounting for imported cases in estimating the time-varying reproductive number of COVID-19 in Hong Kong. J Infect Dis. 2021 Jun 4:jiab299.

  23. Wu P, Liu F, Lin Y, Ren M, Zheng C, Li Y, Peng Z, Qin Y, Yu J, Geng M, Yang X, Zhao H, Li Z, Zhou S, Ran L, Cowling BJ, Lai S, Chen Q, Wang L, Zhaorui Chang, Tsang TK#, Li Z#. Assessing asymptomatic, pre-symptomatic and asymptomatic transmission risk of SARS-CoV-2. Clin Infect Dis. 2021 Mar 27:ciab271

  24. Xin H, Li Y, Wu P, Li Z, Lau EHY, Qin Y, Wang L, Cowling BJ, Tsang TK#, Li Z#. Estimating the latent period of coronavirus disease 2019 (COVID-19). Clin Infect Dis. 2021 Aug 28.ciab746

  25. Lau YC, Tsang TK#, Kennedy-Shaffer L, Kahn R, Lau EHY, Chen D, Wong JY, Ali ST, Wu P, Cowling BJ. Joint estimation of generation time and incubation period for coronavirus disease (COVID-19). J Infect Dis. 2021 Aug 23:jiab424

  26. Yang B, Wu P, Lau EH, Wong JY, Ho F, Gao H, Xiao J, Adam DC, Ng TW, Quan J, Tsang TK, Liao Q, Cowling BJ, Leung GM. Changing disparities in COVID-19 burden in the ethnically homogeneous population of Hong Kong through pandemic waves: an observational study. Clin Infect Dis. 2021 Jan 6

  27. Du Z, Wang L, Yang B, Ali ST, Tsang TK, Shan S, Wu P, Lau EHY, Cowling BJ, Meyers LA. Risk for International Importations of Variant SARS-CoV-2 Originating in the United Kingdom. Emerg Infect Dis. 2021 May;27(5):1527-1529.

  28. Yang B, Tsang TK, Wong JY, He Y, Gao H, Ho F, Lau EH, Wu P, Sullivan SG, Cowling BJ. The differential importation risks of COVID-19 from inbound travellers and the feasibility of targeted travel controls: A case study in Hong Kong. Lancet Reg Health West Pac. 2021 Aug;13:100184.

  29. Gao H, Du Z, Tsang TK, Xiao J, Shan S, Liao Q, Wu P, Leung GM, Cowling BJ. Pandemic fatigue and attenuated impact of avoidance behaviours against COVID-19 transmission in Hong Kong by cross-sectional telephone surveys. BMJ open. 2021 Dec 20;11(12):e055909

  30. Tsang TK, Wu P, Lin Y, Lau EHY, Leung GM, Cowling BJ. Effect of changing case definitions for COVID-19 on the epidemic curve and transmission parameters in mainland China: a modelling study. Lancet Public Health. 2020 May;5(5):e289-e296.

  31. Tsang TK, Lee KH, Foxman B, Balmaseda A, Gresh L, Sanchez N, Ojeda S, Lopez R, Yang Y, Kuan G, Gordon A. Association Between the Respiratory Microbiome and Susceptibility to Influenza Virus Infection Clin Infect Dis. 2020 Aug 22;71(5):1195-1203.

  32. Cowling BJ, Ali ST, Ng TWY, Tsang TK, Li JCM, Fong MW, Liao Q, Kwan MY, Lee SL, Chiu SS, Wu JT, Wu P, Leung GM. Impact assessment of non-pharmaceutical interventions against coronavirus disease 2019 and influenza in Hong Kong: an observational study. Lancet Public Health. 2020 May;5(5):e279-e288.

  33. Adam DC, Wu P, Wong JY, Lau EH, Tsang TK, Cauchemez S, Leung GM, Cowling BJ. Clustering and superspreading potential of SARS-CoV-2 infections in Hong Kong. Nat Med. 2020 Nov;26(11):1714-1719.

  34. Tsang TK, Ghebremariam S, Gresh L, Gordan A, Halloran ME, Kuan G, Balmaseda A, Rojas D, Sugimoto J, Harris E, Longini IM, Yang Y. Effect of exposure history on dengue infection and pathogenicity. Nat Commun. 2019 Mar 18;10(1):1246.

  35. Tsang TK, Fang VJ, Perera RA, Ip DK, Leung GM, Peiris JS, Cauchemez S, Cowling BJ. Indirect protection from vaccinating children against influenza in households. Nat. Commun. 2019; 10, 106.

  36. Wang X, Wu P, Pei Y, Tsang TK, Gu D, Wang W, Zhang J, Horby PW, Uyeki TM, Cowling BJ, Yu H. Assessment of human-to-human transmissibility of avian influenza A(H7N9) virus across five waves by analyzing clusters of case-patients in mainland China, 2013-2017. Clin Infect Dis. 2019; 68: 623-631

  37. Tsang TK, Chen TM, Longini IM, Halloran ME, Wu Y, Yang Y. Transmissibility of Norovirus in Urban Versus Rural Households in a Large Community Outbreak in China. Epidemiology. 2018 Sep;29(5):675-683

  38. Gordon A, Tsang TK, Cowling BJ, Kuan G, Ojeda S, Sanchez N, Gresh L, Lopez R, Balmaseda A, Harris E. Influenza transmission dynamics in Nicaragua households. Emerg Infect Dis. 2018 Oct

  39. Virlogeux V, Feng L, Tsang TK, Jiang H, Fang VJ, Qin Y, Wu P, Wang X, Zheng J, Lau EHY, Peng Z, Yang J, Cowling BJ, Yu H. Evaluation of animal-to-human and human-to-human transmission of influenza A (H7N9) virus in China, 2013-15. Sci Rep. 2018 Jan 11;8(1):552.

  40. Jiang H, Wu P, Uyeki TM, He J, Deng Z, Xu W, Lv Q, Zhang J, Wu Y, Tsang TK, Kang M, Zheng J, Wang L, Yang B, Qin Y, Feng L, Fang VJ, Gao GF, Leung GM, Yu H, Cowling BJ. Preliminary Epidemiologic Assessment of Human Infections with Highly Pathogenic Avian Influenza A(H5N6) Virus, China. Clin Infect Dis. 2017 Aug 1;65(3):383-388

  41. Tsang TK, Lau LL, Cauchemez S, Cowling BJ. Review of household transmission of influenza virus. Trends Microbiol. 2016;24(2):123-33

  42. Tsang TK, Fang VJ, Perera RA, Ip DK, Leung GM, Peiris JS, Cauchemez S, Cowling BJ. Interpreting sero-epidemiological studies for influenza in a context of non-bracketing sera. Epidemiology. 2016;27(1):152-8.

  43. Tsang TK, Cauchemez S, Fang VJ, Chan KH, Ip DK, Leung GM, Peiris JS, Cowling BJ. Individual correlates of infectivity of influenza virus infections in households PLoS One. 2016;11(5):e0154418.

  44. Lai S, Qin Y, Cowling BJ, Ren X, Wardrop NA, Gilbert M, Tsang TK, Wu P, Feng L, Jiang H, Peng Z, Zheng J, Liao Q, Li S, Horby PW, Farrar JJ, Gao GF, Tatem AJ, Yu H. Global epidemiology of avian influenza A H5N1 virus infection in humans, 1997-2015: a systematic review of individual case data. Lancet Infect Dis. 2016. pii: S1473-3099(16)00153-5.

  45. Wong JY, Wu P, Lau EH, Tsang TK, Fang VJ, Ho LM, Cowling BJ. Real-time estimation of the hospitalization fatality risk of influenza A(H1N1)pdm09 in Hong Kong. Epidemiol Infect. 2016;144(8):1579-83.

  46. Virlogeux V, Yang J, Fang VJ, Feng L, Tsang TK, Jiang H, Wu P, Zheng J, Lau EH, Qin Y, Peng Z, Peiris JS, Yu H, Cowling BJ. Association between the Severity of Influenza A(H7N9) Virus Infections and Length of the Incubation Period. PLoS One. 2016;11(2):e0148506.

  47. Wu P, Peng Z, Fang VJ, Feng L, Tsang TK, Jiang H, Lau EH, Yang J, Zheng J, Qin Y, Li Z, Leung GM, Yu H, Cowling BJ. Human Infection with Influenza A(H7N9) Virus during 3 Major Epidemic Waves, China, 2013-2015. Emerg Infect Dis. 2016;22(6):964-72.

  48. Tsang TK, Cowling BJ, Fang VJ, Chan KH, Ip DK, Leung GM, Peiris JS, Cauchemez S. Influenza A virus shedding and infectivity in households. J Infect Dis. 2015;212(9):1420-8.

  49. Qin Y, Horby PW, Tsang TK*, Chen E, Gao L, Ou J, Nguyen TH, Duong TN, Gasimov V, Feng L, Wu P, Jiang H, Ren X, Peng Z, Li S, Li M, Zheng J, Liu S, Hu S, Hong R, Farrar JJ, Leung GM, Gao GF, Cowling BJ, Yu H. Differences in the Epidemiology of Human Cases of Avian Influenza A(H7N9) and A(H5N1) Viruses Infection. Clin Infect Dis. 2015;61(4):563-71.

  50. Cheung DH, Tsang TK, Fang VJ, Xu J, Chan KH, Ip DK, Peiris JS, Leung GM, Cowling BJ. Association of Oseltamivir Treatment With Virus Shedding, Illness, and Household Transmission of Influenza Viruses. J Infect Dis. 2015;212(3):391-6.

  51. Virlogeux V, Li M, Tsang TK, Feng L, Fang VJ, Jiang H, Wu P, Zheng J, Lau EH, Cao Y, Qin Y, Liao Q, Yu H, Cowling BJ. Estimating the Distribution of the Incubation Periods of Human Avian Influenza A(H7N9) Virus Infections. Am J Epidemiol. 2015;182(8):723-9.

  52. Xu C, Chan KH, Tsang TK, Fang VJ, Fung RO, Ip DK, Cauchemez S, Leung GM, Peiris JS, Cowling BJ. Comparative Epidemiology of Influenza B Yamagata- and Victoria-Lineage Viruses in Households. Am J Epidemiol. 2015;182(8):705-13.

  53. Tsang TK, Cauchemez S, Perera RA, Freeman G, Fang VJ, Ip DK, Leung GM, Peiris JS, Cowling BJ. Association between antibody titers and protection against influenza virus infection within households. J Infect Dis. 2014;210(5):684-92.

  54. Wang C, Yu H, Horby P, Cao B, Wu P, Yang S, Gao H, Li H, Tsang TK*, Liao Q, Gao Z, Ip DK, Jia H, Jiang H, Liu B, Ni MY, Dai X, Liu F, Kinh NV, Liem NT, Hien TT, Li Y, Yang J, Wu JT, Zheng Y, Leung GM, Farrar J, Cowling BJ, Uyeki TM, Li L. Comparison of patients hospitalized with influenza A H7N9, H5N1, and 2009 pandemic H1N1. Clin Infect Dis. 2014 ;58(8):1095-103.

  55. Lau EH, Zheng J, Tsang TK, Liao Q, Lewis B, Brownstein JS, Sanders S, Wong JY, Mekaru SR, Rivers C, Wu P, Jiang H, Li Y, Yu J, Zhang Q, Chang Z, Liu F, Peng Z, Leung GM, Feng L, Cowling BJ, Yu H. Accuracy of epidemiological inferences based on publicly available information: retrospective comparative analysis of line lists of human cases infected with influenza A(H7N9) in China. BMC Med. 2014 May 28;12:88.

  56. Liao Q, Ip DK, Tsang TK, Cao B, Jiang H, Liu F, Zheng J, Peng Z, Wu P, Huai Y, Lau EH, Feng L, Leung GM, Yu H, Cowling BJ. A clinical prediction rule for diagnosing human infections with avian influenza A(H7N9) in a hospital emergency department setting. BMC Med. 2014 Aug 5;12:127.

  57. Wu P, Jiang H, Wu JT, Chen E, He J, Zhou H, Wei L, Yang J, Yang B, Qin Y, Fang VJ, Li M, Tsang TK, Zheng J, Lau EH, Cao Y, Chai C, Zhong H, Li Z, Leung GM, Feng L, Gao GF, Cowling BJ, Yu H. Poultry market closures and human infection with influenza A(H7N9) virus, China, 2013-14. Emerg Infect Dis. 2014;20(11):1891-4.

  58. Feng L, Wu JT, Liu X, Yang P, Tsang TK, Jiang H, Wu P, Yang J, Fang VJ, Qin Y, Lau EH, Li M, Zheng J, Peng Z, Xie Y, Wang Q, Li Z, Leung GM, Gao GF, Yu H, Cowling BJ. Clinical severity of human infections with avian influenza A(H7N9) virus, China, 2013/14. Euro Surveill. 2014;19(49). pii: 20984.

  59. Yu H, Cowling BJ, Feng L, Lau EH, Liao Q, Tsang TK, Peng Z, Wu P, Liu F, Fang VJ, Zhang H, Li M, Zeng L, Xu Z, Li Z, Luo H, Li Q, Feng Z, Cao B, Yang W, Wu JT, Wang Y, Leung GM. Human infection with avian influenza A H7N9 virus: an assessment of clinical severity. Lancet. 2013 Jul 13;382(9887):138-45.

  60. Cowling BJ, Jin L, Lau EH, Liao Q, Wu P, Jiang H, Tsang TK, Zheng J, Fang VJ, Chang Z, Ni MY, Zhang Q, Ip DK, Yu J, Li Y, Wang L, Tu W, Meng L, Wu JT, Luo H, Li Q, Shu Y, Li Z, Feng Z, Yang W, Wang Y, Leung GM, Yu H. Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases. Lancet. 2013 Jul 13;382(9887):129-37.